Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | WRN | Q14191 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16132736 | 0.81 | ALDH1A1 (0.39) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL557952 | 0.78 | ALDH1A1 (0.38) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL269178 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL2581743 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL17104477 | 0.76 | ALDH1A1 (0.34) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL28390950 | 0.74 | ALDH1A1 (0.38) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL16862478 | 0.74 | ALDH1A1 (0.38) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL28991876 | 0.74 | ALDH1A1 (0.38) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL9809890 | 0.74 | ALDH1A1 (0.38) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL22203032 | 0.74 | ALDH1A1 (0.38) | ALDH1A1CYP1A2HPGDCYP2C19BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029083-B | Hydrophilic antibody-drug conjugates | 西雅图基因公司 | 2020-02-07 | — | — | CN | claimed |
| CN-106029083-A | Hydrophilic antibody-drug conjugates | 西雅图基因公司 | 2016-10-12 | — | — | CN | claimed |