Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27978560 | 0.81 | LMNA (0.41) | SLC2A1ALDH1A1TLR8TLR7HTT | |
| SCHEMBL1980544 | 0.81 | IGF1R (0.52) | PABPC1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL10133727 | 0.81 | KMT2A (0.57) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL1975113 | 0.81 | NCF1 (0.51) | PABPC1ALDH1A1HTTKMT2ATSHR | |
| SCHEMBL213577 | 0.81 | MYC (0.41) | ALDH1A1TLR8HTTMEN1KMT2A | |
| SCHEMBL28193696 | 0.80 | SLC2A1 (0.56) | SLC2A1ACP1SMN1; SMN2KDM4E | |
| SCHEMBL8646097 | 0.75 | CYP2C9 (0.52) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL557654 | 0.72 | KDM1A (0.53) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL2002464 | 0.71 | HTR1A (0.58) | PABPC1HTTSMN1; SMN2 | |
| SCHEMBL27860753 | 0.71 | KMT2A (0.50) | PABPC1ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074814-A | Glucose transport inhibitor | 拜耳制药股份公司 | 2017-08-18 | — | — | CN | claimed |
| CN-106687455-A | Glucose transport inhibitors | 拜耳制药股份公司 | 2017-05-17 | — | — | CN | claimed |
| CN-106029647-A | Glucose transport inhibitors | 拜耳制药股份公司 | 2016-10-12 | — | — | CN | claimed |
| CN-107074814-A | Glucose transport inhibitor | 拜耳制药股份公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-106687455-A | Glucose transport inhibitors | 拜耳制药股份公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-106029647-A | Glucose transport inhibitors | 拜耳制药股份公司 | 2016-10-12 | — | — | CN | disclosed |