Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 4/20 | 0.76 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.76 |
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | TNKS | O95271 | 3/20 | 0.70 |
| ▸ | TP53 | P04637 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | GABRP | O00591 | 2/20 | 0.70 |
| ▸ | GABRD | O14764 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.70 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.70 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.70 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.70 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.70 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.70 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.70 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.70 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.70 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24227286 | 0.85 | PLA2G2A (0.97) | PLA2G2APLA2G4AHPGDTNKSTP53 | |
| Flavone SCHEMBL30542161 | 0.82 | TNKS (1.00) | PLA2G2APLA2G4AHPGDTNKSTP53 | |
| Flavone SCHEMBL28248986 | 0.82 | TNKS (1.00) | PLA2G2APLA2G4AHPGDTNKSTP53 | |
| Flavone SCHEMBL31316377 | 0.82 | TNKS (1.00) | PLA2G2APLA2G4AHPGDTNKSTP53 | |
| Flavone SCHEMBL15676601 | 0.82 | TNKS (1.00) | PLA2G2APLA2G4AHPGDTNKSTP53 | |
| Flavone SCHEMBL18879 | 0.82 | TNKS (1.00) | PLA2G2APLA2G4AHPGDTNKSTP53 | |
| 6-Aminoflavone SCHEMBL926716 | 0.82 | EGFR (0.82) | PLA2G2APLA2G4AHPGDTNKSTP53 | |
| 6-Aminoflavone SCHEMBL31550004 | 0.82 | EGFR (0.82) | PLA2G2APLA2G4AHPGDTNKSTP53 | |
| 6-Methylflavone SCHEMBL4648879 | 0.82 | TP53 (1.00) | PLA2G2APLA2G4AHPGDTNKSTP53 | |
| SCHEMBL2427741 | 0.82 | TNKS (1.00) | PLA2G2APLA2G4AHPGDTNKSTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106318920-A | Flavones-6-hydroxylase and application thereof to scutellarin synthesis | 中国科学院天津工业生物技术研究所 | 2017-01-11 | — | — | CN | disclosed |