Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.80 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.73 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.73 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.73 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.73 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.73 |
| ▸ | TNKS | O95271 | 4/20 | 0.69 |
| ▸ | PARP1 | P09874 | 2/20 | 0.69 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.69 |
| ▸ | MAOB | P27338 | 1/20 | 0.69 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.69 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 6-Methylflavone SCHEMBL29804485 | 1.00 | TP53 (1.00) | TP53CYP3A4MAPTHPGDKDM4E | |
| SCHEMBL10024074 | 0.90 | CSNK2A2 (0.82) | TP53CYP3A4MAPTHPGDKDM4E | |
| 7-Methylflavone SCHEMBL9137885 | 0.87 | TP53 (0.77) | TP53CYP3A4MAPTHPGDKDM4E | |
| SCHEMBL5433487 | 0.84 | CSNK2A2 (1.00) | TP53CYP3A4MAPTHPGDKDM4E | |
| SCHEMBL4650552 | 0.84 | CSNK2A2 (0.74) | TP53CYP3A4MAPTHPGDKDM4E | |
| Flavone SCHEMBL27560931 | 0.84 | TNKS (0.85) | TP53CYP3A4MAPTHPGDKDM4E | |
| SCHEMBL5424662 | 0.84 | CYP3A4 (0.79) | TP53CYP3A4MAPTHPGDKDM4E | |
| SCHEMBL28043561 | 0.84 | CSNK2A2 (0.72) | TP53CYP3A4MAPTHPGDKDM4E | |
| SCHEMBL24227286 | 0.83 | PLA2G2A (0.97) | TP53CYP3A4MAPTHPGDKDM4E | |
| SCHEMBL28100458 | 0.82 | PLA2G2A (0.76) | TP53CYP3A4MAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113512018-B | Flavonoid compound and preparation method and application thereof | 合肥工业大学 | 2023-07-18 | — | — | CN | claimed |
| US-11596657-B2 | Use of AhR agonist for the preventive or curative treatment of metabolic syndrome and the associated disorders | INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) | 2023-03-07 | — | — | US | claimed |
| US-20220331431-A1 | COMPOSITIONS AND METHODS OF SUPPRESSING AVERSIVENESS OF PHARMACEUTICALS AND INGESTIBLE MATERIALS | MONELL CHEMICAL SENSES CENTRE (US) | 2022-10-20 | — | — | US | claimed |
| CN-109096455-B | Preparation method of modified alkyl phenolic tackifying resin and rubber composition thereof | 山东圣泉新材料股份有限公司 | 2021-07-06 | — | — | CN | claimed |
| WO-2021050449-A1 | COMPOSITIONS AND METHODS OF SUPPRESSING AVERSIVENESS OF PHARMACEUTICALS AND INGESTIBLE MATERIALS | MONELL CHEMICAL SENSES CENTER (US) | 2021-03-18 | — | — | WO | claimed |
| US-20190282638-A1 | USE OF AHR AGONIST FOR THE PREVENTIVE OR CURATIVE TREATMENT OF METABOLIC SYNDROME AND THE ASSOCIATED DISORDERS | INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (FR) | 2019-09-19 | — | — | US | claimed |
| EP-3522902-A1 | USE OF AHR AGONIST FOR THE PREVENTIVE OR CURATIVE TREATMENT OF METABOLIC SYNDROME AND THE ASSOCIATED DISORDERS | Institut National de la Recherche Agronomique (FR) | 2019-08-14 | — | — | EP | claimed |
| WO-2018065132-A1 | USE OF AHR AGONIST FOR THE PREVENTIVE OR CURATIVE TREATMENT OF METABOLIC SYNDROME AND THE ASSOCIATED DISORDERS. | INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) | 2018-04-12 | — | — | WO | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| EP-3522902-B1 | PROBIOTIC BACTERIA PRODUCING AN AHR AGONIST AND THEIR USE IN THE TREATMENT OF METABOLIC SYNDROME AND OBESITY | INSTITUT NATIONAL DE RECH POUR LAGRICULTURE LALIMENTATION ET LENVIRONNEMENT (FR) | 2025-09-03 | — | — | EP | disclosed |
| US-20250263774-A1 | DISCOVERING NEW XENOBIOTIC SUBSTRATES OF AN UDP-GLYCOSYLTRANSFERASE WITH A HIGH-THROUGHPUT METHOD | UNIV NORTH TEXAS (US) | 2025-08-21 | — | — | US | disclosed |
| US-12368049-B2 | Protective film agent and processing method of workpiece | DISCO CORPORATION (JP) | 2025-07-22 | — | — | US | disclosed |
| CN-118638850-A | Application of GmSTOP1-3 gene in regulating anabolism of soybean root flavonoid substances and reducing accumulation of plant ROS | 华南农业大学 | 2024-09-13 | — | — | CN | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220331431-A1 | COMPOSITIONS AND METHODS OF SUPPRESSING AVERSIVENESS OF PHARMACEUTICALS AND INGESTIBLE MATERIALS | HTR6, FOS, API5 | TP53 3455/4885CYP3A4 1429/4885MAPT 3255/4885 |
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | TP53 841/4885CYP3A4 3010/4885MAPT 4313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.