Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26603927 | 1.00 | HPGD (0.47) | HPGDEPHX1HSD17B10NPC1PREP | |
| SCHEMBL27999183 | 0.95 | HSD17B10 (0.48) | HPGDEPHX1HSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL5246013 | 0.88 | HSD17B10 (0.47) | HPGDEPHX1HSD17B10NPC1PREP | |
| SCHEMBL10782598 | 0.88 | HSD17B10 (0.47) | HPGDEPHX1HSD17B10NPC1PREP | |
| SCHEMBL28516773 | 0.84 | HPGD (0.49) | HPGDEPHX1HSD17B10NPC1PREP | |
| SCHEMBL28100905 | 0.84 | HPGD (0.49) | HPGDEPHX1HSD17B10NPC1PREP | |
| SCHEMBL12015364 | 0.81 | RIPK1 (0.41) | HPGDHSD17B10ALDH1A1 | |
| SCHEMBL16352852 | 0.80 | HPGD (0.46) | HPGDEPHX1HSD17B10NPC1PREP | |
| SCHEMBL15221624 | 0.80 | HPGD (0.46) | HPGDEPHX1HSD17B10NPC1PREP | |
| SCHEMBL31197652 | 0.80 | HPGD (0.46) | HPGDEPHX1HSD17B10NPC1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101168514-B | Practical synthesis method for alpha-aminosuberate and alpha-amino suberic acid monoester with optical activity | SHANGHAI YAOMING KANGDE NEW MEDICINE DEVELOPMENT CO., LTD. (CN) | 2011-12-07 | — | — | CN | claimed |
| CN-101168514-A | Practical synthesis method for alpha-aminosuberate and alpha-amino suberic acid monoester with optical activity | SHANGHAI PHARMATECH CO LTD (CN) | 2008-04-30 | — | — | CN | claimed |
| CN-101168514-B | Practical synthesis method for alpha-aminosuberate and alpha-amino suberic acid monoester with optical activity | SHANGHAI YAOMING KANGDE NEW MEDICINE DEVELOPMENT CO., LTD. (CN) | 2011-12-07 | — | — | CN | disclosed |
| CN-101168514-A | Practical synthesis method for alpha-aminosuberate and alpha-amino suberic acid monoester with optical activity | SHANGHAI PHARMATECH CO LTD (CN) | 2008-04-30 | — | — | CN | disclosed |