Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 2/20 | 0.43 |
| ▸ | ALPG | P10696 | 2/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ARG1 | P05089 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440676 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL15436961 | 0.84 | KMT2A (0.60) | ALDH1A1KMT2APOLBCA12CA1 | |
| Oxalic Acid SCHEMBL10364075 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KMT2APOLBCA12CA1 | |
| SCHEMBL992745 | 0.80 | SMN1; SMN2 (0.61) | ALDH1A1KMT2APOLBCA12CA1 | |
| Glycine SCHEMBL28141302 | 0.79 | ESR1 (0.37) | ALPLALPGPLAASMN1; SMN2ESR1 | |
| SCHEMBL26488900 | 0.77 | ALDH1A1 (0.61) | ALDH1A1KMT2APOLBCA12CA1 | |
| SCHEMBL441938 | 0.75 | ALDH1A1 (0.69) | ALDH1A1KMT2APOLBCA12CA1 | |
| SCHEMBL369240 | 0.75 | ALPL (0.54) | ALDH1A1KMT2APOLBALPLALPG | |
| SCHEMBL467176 | 0.75 | — | — | |
| Acetic Acid SCHEMBL28811868 | 0.75 | ALDH1A1 (0.62) | ALDH1A1KMT2APOLBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029053-A | Toothpaste composition | 狮王株式会社 | 2016-10-12 | — | — | CN | disclosed |