Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.54 |
| ▸ | ALPG | P10696 | 2/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | NOS1 | P29475 | 1/20 | 0.51 |
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28835895 | 0.98 | ALPL (0.55) | ALPLALPGALPIPLAAGFER | |
| SCHEMBL28938190 | 0.98 | ALPL (0.53) | ALPLALPGALPIPLAAGFER | |
| SCHEMBL26919072 | 0.84 | ALPL (0.43) | ALPLALPGALPIPLAAGFER | |
| SCHEMBL12735399 | 0.84 | ALPL (0.54) | ALPLALPGALPIPLAAGFER | |
| SCHEMBL1179644 | 0.82 | ALPL (0.53) | ALPLALPGALPIPLAAGFER | |
| SCHEMBL15335282 | 0.81 | ALPL (0.46) | ALPLALPGALPIPLAAGFER | |
| SCHEMBL23286087 | 0.81 | ALPL (0.51) | ALPLALPGALPIPLAAGFER | |
| SCHEMBL992745 | 0.81 | SMN1; SMN2 (0.61) | ALPLALPGALPIPLAAGFER | |
| SCHEMBL4298080 | 0.81 | ALPL (0.51) | ALPLALPGALPIPLAAGFER | |
| SCHEMBL25401370 | 0.81 | ALPL (0.51) | ALPLALPGALPIPLAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108993607-B | Cu2Method for preparing aldehyde by air oxidation of alcohol under catalysis of S/imidazole compound/TEMPO | 嘉兴学院 | 2021-09-17 | — | — | CN | claimed |
| US-20230014907-A1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED | 2023-01-19 | — | — | US | disclosed |
| US-20230011118-A1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED | 2023-01-12 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-3939972-A1 | TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS | Molecular Insight Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |
| WO-2021252859-A1 | INHIBITORS OF APOL1 AND USE OF THE SAME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2021-12-16 | — | — | WO | disclosed |
| WO-2021252849-A1 | INHIBITORS OF APOL1 AND USE OF THE SAME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2021-12-16 | — | — | WO | disclosed |
| EP-3545978-B1 | TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS | MOLECULAR INSIGHT PHARM INC (US) | 2021-09-08 | — | — | EP | disclosed |
| CN-105733611-B | Liquid crystal aligning agent, method for producing liquid crystal element, liquid crystal alignment film, and liquid crystal element | JSR株式会社 | 2020-03-13 | — | — | CN | disclosed |
| EP-3545978-A1 | TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS | Molecular Insight Pharmaceuticals, Inc. (US) | 2019-10-02 | — | — | EP | disclosed |
| EP-0751424-B1 | Silver halide color photographic material and method for forming image | FUJI PHOTO FILM CO LTD (JP) | 2000-05-31 | — | — | EP | disclosed |
| US-5989789-A | COLOR DEVELOPMENT CARRIED UNDER SPECIFIC DEVELOPING TIMES AND TEMPERATURE; USING A COLOR DEVELOPING SOLUTION WHERE THE SILVER HALIDE SOLVENT IS SELECTED FROM THIOSULFATE, METHANESULFONATE, THIOCYANATE, AND OTHERS OF GIVEN FORMULAS | FUJI PHOTO FILM CO., LTD. (JP) | 1999-11-23 | — | — | US | disclosed |
| US-5985527-A | IMAGES AND DYE DEVELOPMENT | FUJI PHOTO FILM CO., LTD. (JP) | 1999-11-16 | — | — | US | disclosed |
| US-5882847-A | SUITABLE FOR RAPID PROCESSING; MAGNETIC RECORDING MEDIA | FUJI PHOTO FILM CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0751424-A2 | Silver halide color photographic material and method for forming image | FUJI PHOTO FILM CO., LTD. (JP) | 1997-01-02 | — | — | EP | disclosed |
| EP-0726493-A2 | Silver halide color photographic material and image forming method using the same | FUJI PHOTO FILM CO., LTD. (JP) | 1996-08-14 | — | — | EP | disclosed |
| US-5324731-A | Method of inhibiting transformation of cells in which purine metabolic enzyme activity is elevated | AMIRA, INC. (US) | 1994-06-28 | — | — | US | disclosed |
| US-5321030-A | Administering for treatment or prevention | AMIRA, INC. (US) | 1994-06-14 | — | — | US | disclosed |
| EP-0557383-A1 | METHOD OF INHIBITING TRANSFORMATION, GROWTH AND METASTASIS OF CELLS IN WHICH PURINE METABOLIC ENZYME ACTIVITY IS ELEVATED | AMIRA, INC. (US) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992008456-A2 | METHOD OF INHIBITING TRANSFORMATION, GROWTH AND METASTASIS OF CELLS IN WHICH PURINE METABOLIC ENZYME ACTIVITY IS ELEVATED | AMIRA, INC. (US) | 1992-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230014907-A1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | APOL1, APOB, NPC1L1 | ALPL 340/4885ALPG 2155/4885ALPI 492/4885 |
| US-20230011118-A1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | APOL1, APOB, SAAL1 | ALPL 237/4885ALPG 2243/4885ALPI 586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.