Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28834742 | 1.00 | CTSK (0.48) | CTSKCTSSACEPPARAPPARG | |
| SCHEMBL28102485 | 0.81 | PPARA (0.43) | CTSKCTSSACEPPARAPPARG | |
| SCHEMBL19720147 | 0.81 | PPARA (0.43) | CTSKCTSSACEPPARAPPARG | |
| SCHEMBL12305800 | 0.80 | CTSK (0.56) | CTSKCTSSACEPPARAPPARG | |
| SCHEMBL10151226 | 0.80 | CTSK (0.56) | CTSKCTSSACEPPARAPPARG | |
| SCHEMBL181775 | 0.79 | CTSK (0.71) | CTSKCTSSACEPPARAPPARG | |
| SCHEMBL181807 | 0.79 | CTSK (0.71) | CTSKCTSSACEPPARAPPARG | |
| SCHEMBL181808 | 0.79 | CTSK (0.71) | CTSKCTSSACEPPARAPPARG | |
| SCHEMBL344068 | 0.76 | CTSK (0.63) | CTSKCTSSACEPPARAPPARG | |
| SCHEMBL19605638 | 0.76 | CTSK (0.63) | CTSKCTSSACEPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102786476-B | compounds as opioid receptor modulators | 詹森药业有限公司 | 2017-01-18 | — | — | CN | disclosed |