Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | ULK1 | O75385 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28056642 | 0.90 | KDM4E (0.50) | ALDH1A1KDM4ESMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL27711470 | 0.85 | KDM4E (0.47) | ALDH1A1KDM4ESMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL6886046 | 0.83 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2HSD17B10NPC1LMNA | |
| SCHEMBL655728 | 0.76 | PBRM1 (0.52) | ALDH1A1KDM4ESMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL11183467 | 0.76 | ALDH1A1 (0.55) | ALDH1A1KDM4ESMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL27889653 | 0.75 | HDAC1 (0.53) | ALDH1A1KDM4ESMN1; SMN2NPSR1NPC1 | |
| SCHEMBL27354565 | 0.75 | ALDH1A1 (0.71) | ALDH1A1KDM4ESMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL658648 | 0.75 | L3MBTL1 (0.69) | ALDH1A1KDM4ESMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL29944886 | 0.74 | KDM4E (0.62) | ALDH1A1KDM4ESMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL5906529 | 0.74 | KDM4E (0.62) | ALDH1A1KDM4ESMN1; SMN2NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102844327-B | Template-fixed peptidomimetics with CXCR7 modulatory activity | 波利弗尔股份公司 | 2016-10-26 | — | — | CN | disclosed |