Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28102641 | 0.85 | ALDH1A1 (0.54) | KDM4EALDH1A1KDM4CADRB2ADRB1 | |
| SCHEMBL28056642 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1KDM4CHSD17B10SMN1; SMN2 | |
| SCHEMBL26716442 | 0.77 | SMN1; SMN2 (0.62) | KDM4EALDH1A1KDM4CHSD17B10GAA | |
| SCHEMBL3650360 | 0.75 | NPSR1 (0.59) | KDM4EALDH1A1KDM4CADRB2ADRB1 | |
| SCHEMBL7090374 | 0.74 | GAA (0.78) | KDM4EALDH1A1KDM4CADRB2ADRB1 | |
| SCHEMBL11183467 | 0.73 | ALDH1A1 (0.55) | KDM4EALDH1A1KDM4CHSD17B10KMT2A | |
| SCHEMBL27354565 | 0.72 | ALDH1A1 (0.71) | KDM4EALDH1A1KDM4CADRB2ADRB1 | |
| SCHEMBL28280197 | 0.71 | ADRB2 (0.56) | KDM4EALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL8534801 | 0.71 | L3MBTL1 (0.57) | KDM4EALDH1A1HSD17B10KMT2APOLB | |
| SCHEMBL7900184 | 0.70 | PRSS1 (0.53) | KDM4EALDH1A1HSD17B10KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101133060-A | Enzyme inhibitors | CHROMA THERAPEUTICS LTD (GB) | 2008-02-27 | — | — | CN | disclosed |