Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822593 | 0.93 | VCAM1 (0.51) | VCAM1POLBAKR1C3NPC1RAB9A | |
| SCHEMBL11321781 | 0.92 | AKR1C3 (0.47) | VCAM1POLBAKR1C3NPC1RAB9A | |
| SCHEMBL15608393 | 0.89 | POLB (0.52) | VCAM1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11320176 | 0.82 | NR4A1 (0.50) | VCAM1POLBNPC1SMN1; SMN2KMT2A | |
| SCHEMBL28309348 | 0.82 | VCAM1 (0.40) | VCAM1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10902716 | 0.82 | VCAM1 (0.56) | VCAM1POLBAKR1C3NPC1RAB9A | |
| Toluene SCHEMBL28853124 | 0.82 | ALDH1A1 (0.50) | NPC1RAB9ASMN1; SMN2LMNADCTPP1 | |
| SCHEMBL11002006 | 0.82 | LMNA (0.47) | VCAM1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL11329074 | 0.81 | MAPK1 (0.51) | POLBRAB9AKMT2ALMNAMEN1 | |
| SCHEMBL17030649 | 0.81 | ALDH1A1 (0.56) | POLBAKR1C3NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980381-A | Substituted uracils and use thereof | 拜耳医药股份有限公司 | 2016-09-28 | — | — | CN | disclosed |