Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468449 | 0.81 | GAA (0.48) | ALDH1A1L3MBTL1GAAMGAMSI | |
| SCHEMBL7713280 | 0.78 | GAA (0.55) | ALDH1A1L3MBTL1GAAMGAMSI | |
| SCHEMBL28164018 | 0.77 | ALDH1A1 (0.37) | ALDH1A1TSHRGAAMGAMSI | |
| SCHEMBL35720 | 0.77 | — | — | |
| Dimethylamine SCHEMBL444411 | 0.75 | ALDH1A1 (0.47) | ALDH1A1TSHRGAAMGAMSI | |
| SCHEMBL6916163 | 0.75 | EPHX1 (0.36) | ALDH1A1LMNANFKB1 | |
| Methyl Alcohol SCHEMBL29084611 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TSHRGAAMGAMSI | |
| SCHEMBL3105866 | 0.74 | CTSD (0.33) | ALDH1A1 | |
| SCHEMBL8928249 | 0.74 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1TSHRGAAMGAM | |
| SCHEMBL1923846 | 0.73 | ALDH1A1 (0.37) | ALDH1A1TSHRSOAT1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104395310-B | Bicyclic substituted uracils and their use | 拜耳药业股份公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-105980381-A | Substituted uracils and use thereof | 拜耳医药股份有限公司 | 2016-09-28 | — | — | CN | disclosed |