SCHEMBL6468449

SCHEMBL6468449

CCOC(=O)NC(=O)OC(=O)NC(=O)OCC

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.48
MGAM O43451 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
SOAT1 P35610 1/20 0.48
ALDH1A1 P00352 6/20 0.46
LMNA P02545 1/20 0.43
HSD17B10 Q99714 1/20 0.43
ALOX15 P16050 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KDM4E B2RXH2 1/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7713280 0.92 GAA (0.55) GAAMGAMSIMGAM2SOAT1
SCHEMBL6958990 0.84 GAA (0.48) GAAMGAMSIMGAM2SOAT1
SCHEMBL9865139 0.82 GAA (0.46) GAAMGAMSIMGAM2SOAT1
SCHEMBL944132 0.81 GAA (0.50) GAAMGAMSIMGAM2SOAT1
SCHEMBL697911 0.81
SCHEMBL28103296 0.81 ALDH1A1 (0.38) GAAMGAMSIMGAM2SOAT1
SCHEMBL9863845 0.81 TSHR (0.41) GAAMGAMSIMGAM2SOAT1
SCHEMBL6958983 0.80 GAA (0.44) GAAMGAMSIMGAM2SOAT1
SCHEMBL2105768 0.79
SCHEMBL1413000 0.79 GAA (0.48) GAAMGAMSIMGAM2SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114131923-B Method for producing polyurethane three-dimensional objects from materials having multiple hardening mechanisms 卡本有限公司 2024-05-24 CN disclosed
CN-111194217-B 4 '-fluoro-2' -methyl substituted nucleoside derivatives as inhibitors of HCV RNA replication 里伯赛恩斯有限责任公司 2024-01-12 CN disclosed
CN-115195104-B Dual precursor resin system for additive manufacturing with dual cure resins 卡本有限公司 2023-12-05 CN disclosed
CN-115195104-A Dual precursor resin system for additive manufacturing with dual cure resins 卡本有限公司 2022-10-18 CN disclosed
CN-114734628-A Method for producing three-dimensional objects from materials with multiple hardening mechanisms 卡本有限公司 2022-07-12 CN disclosed
CN-108139665-B Dual precursor resin system for additive manufacturing with dual cure resins 卡本有限公司 2022-07-05 CN disclosed
CN-114131923-A Method for producing three-dimensional objects of polyurethane from materials with multiple hardening mechanisms 卡本有限公司 2022-03-04 CN disclosed
CN-106687861-B Method for producing three-dimensional objects from materials with multiple hardening mechanisms 卡本有限公司 2022-01-11 CN disclosed
CN-106796392-B Method for producing three-dimensional objects of polyurethane from materials with multiple hardening mechanisms 卡本有限公司 2021-12-14 CN disclosed
CN-107077064-B Polyurethane resin with multiple hardening mechanisms for producing three-dimensional objects 卡本有限公司 2021-06-04 CN disclosed
CN-102498113-A Macrocyclic inhibitors of jak HOFFMANN LA ROCHE 2012-06-13 CN disclosed
CN-102482326-A Method for isolating therapeutic peptides CORDEN PHARMA COLORADO INC 2012-05-30 CN disclosed
CN-102414220-A Insulinotropic peptide synthesis using solid and liquid phase combination techniques HOFFMANN LA ROCHE 2012-04-11 CN disclosed
CN-101903400-A Insulinotropic peptide synthesis using solid and liquid phase combination techniques HOFFMANN LA ROCHE 2010-12-01 CN disclosed
CN-101646679-A Heterocyclic antiviral compounds HOFFMANN LA ROCHE CH 2010-02-10 CN disclosed
CN-101560167-A Alpha-n-methylation of amino acids HOFFMANN LA ROCHE (CH) 2009-10-21 CN disclosed
CN-101384599-A Heterocyclic antiviral compounds HOFFMANN LA ROCHE (CH) 2009-03-11 CN disclosed
CN-101384596-A Heterocylic antiviral compounds HOFFMANN LA ROCHE (CH) 2009-03-11 CN disclosed
CN-1878783-A Process for preparing antiviral nucleoside derivatives ROCHE PALO ALTO LLC (CH) 2006-12-13 CN disclosed
US-20050080252-A1 Process for preparing antiviral nucleoside derivatives ROCHE PALO ALTO LLC 2005-04-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080252-A1 Process for preparing antiviral nucleoside derivatives UMPS, ADAR, DUT GAA 1423/4885MGAM 2559/4885SI 71/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.