SCHEMBL28103402

SCHEMBL28103402

CC1(C)c2cc(Br)ccc2Cc2ccc(Br)cc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CMA1 P23946 1/20 0.42
AHR P35869 1/20 0.42
PGR P06401 2/20 0.41
TDP2 O95551 1/20 0.40
KDM1A O60341 1/20 0.39
CHEK2 O96017 1/20 0.38
ROS1 P08922 1/20 0.38
MARK3 P27448 1/20 0.38
LTK P29376 1/20 0.38
FLT4 P35916 1/20 0.38
KDR P35968 1/20 0.38
MINK1 Q8N4C8 1/20 0.38
AURKB Q96GD4 1/20 0.38
PBK Q96KB5 1/20 0.38
STK17A Q9UEE5 1/20 0.38
MAP4K5 Q9Y4K4 1/20 0.38
BRD4 O60885 1/20 0.38
METAP1 P53582 1/20 0.37
TRPA1 O75762 1/20 0.37
HTR2A P28223 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20212018 0.78 CYP2A6 (0.35) CMA1AHRKDM1A
SCHEMBL12721438 0.78 CYP2A6 (0.35) CMA1AHRKDM1A
SCHEMBL27965450 0.78 SIRT1 (0.35) CMA1AHRPGRTDP2
SCHEMBL7796330 0.77 CMA1 (0.47) CMA1AHRPGRTDP2KDM1A
SCHEMBL204806 0.76 PDK2 (0.44) PGRTDP2KDM1AMETAP1HTR2B
SCHEMBL29403081 0.76 PDK2 (0.44) PGRTDP2KDM1AMETAP1HTR2B
SCHEMBL29587737 0.76 PDK2 (0.44) PGRTDP2KDM1AMETAP1HTR2B
SCHEMBL17808124 0.74 CMA1 (0.44) CMA1AHRPGRTDP2KDM1A
SCHEMBL4234542 0.73 TDP1 (0.45) CMA1AHRPGRTDP2CHEK2
SCHEMBL2452451 0.73 LMNA (0.42) CMA1AHRPGRBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106008537-A Bipolar body organic electroluminescent material and application thereof 中节能万润股份有限公司 2016-10-12 CN claimed