Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | MAX | P61244 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2773030 | 0.93 | AR (0.55) | ARPELP1MEN1ALDH1A1KMT2A | |
| SCHEMBL2770938 | 0.88 | USP2 (0.51) | ALDH1A1XDHSMN1; SMN2 | |
| SCHEMBL10946588 | 0.84 | MAPT (0.60) | MAPTMEN1ALDH1A1KMT2ARECQL | |
| SCHEMBL4718892 | 0.83 | AR (0.67) | ARPELP1MEN1ALDH1A1KMT2A | |
| SCHEMBL28451159 | 0.81 | MYC (0.58) | ARPELP1ALDH1A1MYCMAX | |
| SCHEMBL4717487 | 0.80 | MYC (0.64) | XDHMYCMAXPRSS1 | |
| SCHEMBL17395859 | 0.80 | ALDH1A1 (0.59) | ARPELP1MAPTALDH1A1KMT2A | |
| SCHEMBL4717489 | 0.79 | PDK1 (0.52) | ARPELP1XDHMYCMAX | |
| SCHEMBL3981486 | 0.77 | KMT2A (0.45) | ARPELP1MAPTALDH1A1KMT2A | |
| SCHEMBL4718483 | 0.77 | XDH (0.47) | ARPELP1XDHMYCMAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193125-A2 | OXADIAZOLE DERIVATIVES | Merck Serono S.A. (CH) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009043889-A2 | OXADIAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2009-04-09 | — | — | WO | disclosed |