Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.67 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.53 |
| ▸ | MYC | P01106 | 1/20 | 0.53 |
| ▸ | MAX | P61244 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155524 | 0.90 | AR (0.55) | ARPELP1ALDH1A1HPGDNPSR1 | |
| SCHEMBL2773030 | 0.90 | AR (0.55) | ARPELP1ALDH1A1MYCMAX | |
| SCHEMBL28876130 | 0.87 | ALDH1A1 (0.53) | ARPELP1ALDH1A1HPGDNPSR1 | |
| SCHEMBL28451159 | 0.87 | MYC (0.58) | ARPELP1ALDH1A1MYCMAX | |
| SCHEMBL17395859 | 0.86 | ALDH1A1 (0.59) | ARPELP1ALDH1A1HPGDMYC | |
| SCHEMBL4717487 | 0.86 | MYC (0.64) | MYCMAXXDHEP300HIF1A | |
| SCHEMBL4717489 | 0.85 | PDK1 (0.52) | ARPELP1MYCMAXXDH | |
| SCHEMBL17512389 | 0.85 | GAA (0.64) | ALDH1A1HPGDNPSR1VCAM1KMT2A | |
| SCHEMBL2810372 | 0.83 | AR (0.49) | ARPELP1ALDH1A1MYCMAX | |
| SCHEMBL5913915 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HPGDNPSR1VCAM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452528-B1 | XANTHINE OXIDASE INHIBITORS | NIPPON CHEMIPHAR CO (JP) | 2008-08-13 | — | — | EP | disclosed |
| CN-101092400-A | Xanthine oxidase inhibitor | NIPPON CHEMIPHAR CO (JP) | 2007-12-26 | — | — | CN | disclosed |
| US-20070265283-A1 | Xanthine Oxidase Inhibitor | NIPPON CHEMIPHAR CO., LTD. | 2007-11-15 | — | — | US | disclosed |
| CN-100338040-C | xanthine oxidase inhibiting compounds | NIPPON CHEMIPHAR CO (JP) | 2007-09-19 | — | — | CN | disclosed |
| US-7253154-B2 | Substituted thiazolopyrimidines as xanthine oxidase inhibitors | NIPPON CHEMIPHAR CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| CN-1615299-A | Xanthine oxidase inhibitors | NIPPON CHEMIPHAR CO (JP) | 2005-05-11 | — | — | CN | disclosed |
| US-20050090472-A1 | Xanthine oxidase inhibitors | NIPPON CHEMIPHAR CO., LTD. (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1452528-A1 | XANTHINE OXIDASE INHIBITORS | NIPPON CHEMIPHAR CO., LTD. (JP) | 2004-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090472-A1 | Xanthine oxidase inhibitors | XDH, CBR1, NOX1 | AR 1893/4885PELP1 2697/4885ALDH1A1 706/4885 |
| US-20070265283-A1 | Xanthine Oxidase Inhibitor | XDH, CBR1, NOX1 | AR 1841/4885PELP1 2667/4885ALDH1A1 671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.