Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DDO | Q99489 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | SELL | P14151 | 1/20 | 0.39 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16881474 | 0.89 | RECQL (0.49) | RECQLCYP2C9CYP2C19SMN1; SMN2KMT2A | |
| SCHEMBL28105209 | 0.86 | KMT2A (0.60) | SMN1; SMN2KMT2AKDM4EALDH1A1NR1H4 | |
| SCHEMBL4403052 | 0.79 | MEN1 (0.52) | CYP2C9CYP2C19SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL8138199 | 0.77 | KMT2A (0.67) | CYP2C9CYP2C19KMT2AALDH1A1MEN1 | |
| SCHEMBL16881310 | 0.75 | KMT2A (0.60) | SMN1; SMN2KMT2AKDM4EALDH1A1NR1H4 | |
| SCHEMBL16880735 | 0.75 | KLKB1 (0.48) | RECQLCYP2C9CYP2C19ALDH1A1DYRK1A | |
| SCHEMBL23316731 | 0.71 | NR1H4 (0.58) | RECQLKMT2ANR1H4 | |
| SCHEMBL27697868 | 0.71 | HCAR2 (0.53) | CYP2C9CYP2C19SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL28105244 | 0.71 | HCAR2 (0.53) | CYP2C9CYP2C19KMT2AKDM4EALDH1A1 | |
| SCHEMBL28105254 | 0.70 | HCAR2 (0.42) | CYP2C9CYP2C19SMN1; SMN2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061480-A | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2016-10-26 | — | — | CN | disclosed |