Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | DHPS | P49366 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30719400 | 0.83 | CYP11B1 (0.51) | TP53MAPTKLKB1LMNACYP11B1 | |
| SCHEMBL21527215 | 0.83 | MAPT (0.56) | TP53MAPTKLKB1LMNAL3MBTL1 | |
| SCHEMBL7614386 | 0.83 | KDM4C (0.50) | TP53MAPTKDM4CDHPSCYP11B1 | |
| SCHEMBL7617006 | 0.81 | CYP11B1 (0.54) | KDM4CDHPSCYP11B1CYP11B2CYP19A1 | |
| SCHEMBL21201591 | 0.80 | NPBWR1 (0.40) | TP53MAPTKLKB1LMNAL3MBTL1 | |
| SCHEMBL22148839 | 0.77 | KLKB1 (0.37) | TP53MAPTKLKB1LMNAL3MBTL1 | |
| SCHEMBL24754230 | 0.75 | TBXAS1 (0.43) | KLKB1CYP19A1ALDH1A1 | |
| SCHEMBL28105189 | 0.74 | POLB (0.54) | TP53MAPTKLKB1L3MBTL1ALDH1A1 | |
| SCHEMBL16881377 | 0.71 | KLKB1 (0.40) | KLKB1LMNAL3MBTL1KDM4CCYP11B1 | |
| SCHEMBL4220909 | 0.68 | CYP3A4 (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061480-A | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2016-10-26 | — | — | CN | disclosed |