Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.54 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.48 |
| ▸ | DHPS | P49366 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614386 | 0.90 | KDM4C (0.50) | CYP11B1CYP11B2CYP19A1DHPSIDO1 | |
| SCHEMBL28105272 | 0.81 | TP53 (0.36) | CYP11B1CYP11B2CYP19A1DHPSKDM4C | |
| SCHEMBL21527215 | 0.81 | MAPT (0.56) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL30719400 | 0.81 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL21201591 | 0.77 | NPBWR1 (0.40) | — | |
| SCHEMBL22148839 | 0.75 | KLKB1 (0.37) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL16881377 | 0.75 | KLKB1 (0.40) | CYP11B1CYP11B2KDM4C | |
| SCHEMBL24754230 | 0.73 | TBXAS1 (0.43) | CYP19A1HDAC6 | |
| SCHEMBL14476554 | 0.71 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP17A1CYP19A1FAAH | |
| SCHEMBL17677819 | 0.71 | GRK2 (0.65) | CYP11B1CYP11B2DHPSKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436933-B1 | 1-HYDROXY-3-(2-METHYLPROPYL)-5,6-DIPHENYLHYDROPYRAZIN-2-ONE | STRUCTURAL BIOINFORMATICS INC. | 2002-08-20 | — | — | US | disclosed |