Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21527215 | 0.83 | MAPT (0.56) | CYP11B1CYP11B2CYP19A1MAPTTHRB | |
| SCHEMBL28105272 | 0.83 | TP53 (0.36) | CYP11B1CYP11B2CYP19A1MAPTPKM | |
| SCHEMBL7614386 | 0.83 | KDM4C (0.50) | CYP11B1CYP11B2CYP19A1MAPTDYRK1A | |
| SCHEMBL7617006 | 0.81 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL21201591 | 0.80 | NPBWR1 (0.40) | MAPTHTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22148839 | 0.77 | KLKB1 (0.37) | CYP11B1CYP11B2CYP19A1MAPTLMNA | |
| SCHEMBL1240350 | 0.75 | MAPT (0.56) | CYP11B1CYP11B2MAPTTHRBHTT | |
| SCHEMBL24754230 | 0.75 | TBXAS1 (0.43) | CYP19A1ALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL16881377 | 0.74 | KLKB1 (0.40) | CYP11B1CYP11B2NPSR1LMNAPOLB | |
| SCHEMBL28617449 | 0.70 | GRM2 (0.52) | CYP11B1CYP11B2CYP19A1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513020-B | KDM1A inhibitors for the treatment of diseases | 伊美格生物科学公司 | 2024-02-23 | — | — | CN | disclosed |