Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1918754 | 0.86 | PIM1 (0.52) | PIM1HSD11B1BCAT1FLT3TAS1R3 | |
| SCHEMBL29463590 | 0.81 | KDM4E (0.69) | HSD11B1MAPTKDM4ELMNATP53 | |
| SCHEMBL446971 | 0.81 | TAS1R3 (0.64) | BCAT1FLT3TAS1R3TAS1R1MAPT | |
| SCHEMBL2081885 | 0.78 | HSD11B1 (0.59) | PIM1HSD11B1MAPTCASP3SENP7 | |
| SCHEMBL7799411 | 0.77 | HSD11B1 (0.49) | PIM1HSD11B1FLT3TAS1R3TAS1R1 | |
| SCHEMBL8696625 | 0.77 | FLT3 (0.76) | PIM1FLT3TAS1R3TAS1R1MAPT | |
| SCHEMBL3316267 | 0.77 | STS (0.49) | HSD11B1MAPTKDM4ECA2LMNA | |
| SCHEMBL17161458 | 0.77 | PIM1 (0.68) | PIM1MAPTCASP3SENP7TDP1 | |
| SCHEMBL18001830 | 0.77 | HSD11B1 (0.58) | HSD11B1MAPTKDM4ECA2TP53 | |
| SCHEMBL9048693 | 0.76 | PIM1 (0.49) | PIM1FLT3TAS1R3TAS1R1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111646889-B | Green synthesis method of drug active molecules GC-24 and furaldehyde | 兰州大学 | 2023-01-31 | — | — | CN | claimed |
| CN-111646889-A | Green synthesis method of drug active molecules GC-24 and furaldehyde | 兰州大学 | 2020-09-11 | — | — | CN | claimed |
| CN-111646889-B | Green synthesis method of drug active molecules GC-24 and furaldehyde | 兰州大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-111646889-A | Green synthesis method of drug active molecules GC-24 and furaldehyde | 兰州大学 | 2020-09-11 | — | — | CN | disclosed |
| US-20100249179-A1 | Farnesoid X Receptor Agonists | SMITHKLINE BEECHAM CORPORATION (US) | 2010-09-30 | — | — | US | disclosed |
| US-20100249179-A1 | Farnesoid X Receptor Agonists | SMITHKLINE BEECHAM CORPORATION (US) | 2010-09-30 | — | — | US | disclosed |
| US-20100249179-A1 | Farnesoid X Receptor Agonists | SMITHKLINE BEECHAM CORPORATION (US) | 2010-09-30 | — | — | US | disclosed |
| EP-2170072-A1 | FARNESOID X RECEPTOR AGONISTS | GlaxoSmithKline LLC (US) | 2010-04-07 | — | — | EP | disclosed |
| WO-2008157270-A1 | FARNESOID X RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249179-A1 | Farnesoid X Receptor Agonists | NR1H4, NR1H3, NR1H2 | PIM1 4490/4885HSD11B1 105/4885BCAT1 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.