Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | LIMK2 | P53671 | 4/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28106979 | 0.86 | NR3C1 (0.49) | NR3C1MTNR1AMTNR1BLIMK2LIMK1 | |
| SCHEMBL18138845 | 0.74 | PFKFB3 (0.51) | NR3C1MTNR1AMTNR1BPTGESLIMK2 | |
| SCHEMBL18300922 | 0.73 | MTNR1A (0.41) | NR3C1MTNR1AMTNR1BPTGESLIMK2 | |
| SCHEMBL18300923 | 0.73 | PLAU (0.43) | NR3C1MTNR1AMTNR1BPTGESLIMK2 | |
| SCHEMBL28106666 | 0.73 | NR3C1 (0.52) | NR3C1LIMK2HTR6ALDH1A1 | |
| SCHEMBL18138726 | 0.73 | MTNR1A (0.57) | NR3C1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL28107051 | 0.72 | NR3C1 (0.46) | NR3C1MTNR1AMTNR1BLIMK2LIMK1 | |
| SCHEMBL1403074 | 0.71 | PGR (0.75) | BRD4HSD17B2PGRHTR6ALDH1A1 | |
| SCHEMBL30565215 | 0.71 | PGR (0.75) | BRD4HSD17B2PGRHTR6ALDH1A1 | |
| SCHEMBL28106702 | 0.71 | NR3C1 (0.45) | NR3C1MTNR1AMTNR1BLIMK2LIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029633-A | Sulfonamide derivative or pharmaceutically acceptable acid addition salt thereof | 国立大学法人筑波大学 | 2016-10-12 | — | — | CN | disclosed |