Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RPA1 | P27694 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28107051 | 0.86 | NR3C1 (0.46) | NR3C1MAPTTP53MTNR1AMTNR1B | |
| SCHEMBL28106677 | 0.86 | NR3C1 (0.49) | NR3C1MTNR1AMTNR1BALDH1A1LIMK2 | |
| SCHEMBL28106666 | 0.79 | NR3C1 (0.52) | NR3C1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL18138792 | 0.78 | HCRTR2 (0.46) | NR3C1MAPTMTNR1AMTNR1BGAA | |
| SCHEMBL20578438 | 0.77 | ALDH1A1 (0.46) | NR3C1MAPTKMT2AGAAMEN1 | |
| SCHEMBL28106702 | 0.76 | NR3C1 (0.45) | NR3C1MAPTTP53MTNR1AMTNR1B | |
| SCHEMBL28106651 | 0.74 | LMNA (0.57) | NR3C1MAPTTP53KMT2AGAA | |
| SCHEMBL20578323 | 0.72 | LMNA (0.64) | NR3C1MAPTTP53KMT2AGAA | |
| SCHEMBL18300922 | 0.71 | MTNR1A (0.41) | NR3C1MTNR1AMTNR1BLIMK2LIMK1 | |
| SCHEMBL20578446 | 0.71 | SMN1; SMN2 (0.45) | MAPTKMT2AGAAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029633-A | Sulfonamide derivative or pharmaceutically acceptable acid addition salt thereof | 国立大学法人筑波大学 | 2016-10-12 | — | — | CN | disclosed |