Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | DRD4 | P21917 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1606405 | 0.92 | GSK3B (0.44) | CYP11B2HTR6DRD2DRD4DRD3 | |
| SCHEMBL1605594 | 0.88 | PRMT6 (0.45) | CYP11B2ALDH1A1GSK3BDYRK1APRMT6 | |
| SCHEMBL7947805 | 0.80 | CYP11B2 (0.46) | CYP11B2AOC3CYP19A1CYP11B1CHRNB1 | |
| SCHEMBL1606382 | 0.80 | CYP11B2 (0.46) | CYP11B2AOC3CYP19A1CYP11B1CHRNB1 | |
| SCHEMBL1607050 | 0.77 | CYP11B2 (0.74) | CYP11B2ALDH1A1DYRK1AAOC3CYP19A1 | |
| SCHEMBL30386058 | 0.77 | CYP11B2 (0.74) | CYP11B2ALDH1A1DYRK1AAOC3CYP19A1 | |
| SCHEMBL412750 | 0.77 | CHRNB1 (0.49) | CYP11B2DRD2DRD4DRD3GSK3B | |
| SCHEMBL1605318 | 0.77 | KDM4E (0.42) | CYP11B2ALOX15 | |
| SCHEMBL28107219 | 0.76 | CYP11B2 (0.67) | CYP11B2DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL1606105 | 0.75 | CYP11B2 (0.47) | CYP11B2AOC3CYP19A1CYP11B1CHRNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104193725-B | Organic compound | 诺华股份有限公司 | 2016-11-16 | — | — | CN | disclosed |