Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.49 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1606572 | 0.83 | PTGES2 (0.52) | TBXAS1PTGES2PPARG | |
| Hydrochloric Acid SCHEMBL11006604 | 0.83 | PTGES2 (0.51) | TBXAS1PTGES2PPARG | |
| SCHEMBL1605685 | 0.82 | TBXAS1 (0.49) | TBXAS1PTGES2CYP11B1CYP11B2MAOA | |
| SCHEMBL1604760 | 0.81 | CCR2 (0.51) | TBXAS1PTGES2PPARGL3MBTL1TACR1 | |
| SCHEMBL1606071 | 0.80 | TBXAS1 (0.64) | TBXAS1PTGES2CYP11B1CYP11B2MAOA | |
| SCHEMBL1605764 | 0.79 | TBXAS1 (0.51) | TBXAS1PTGES2CYP11B1CYP11B2MAOA | |
| SCHEMBL1605397 | 0.79 | TBXAS1 (0.54) | TBXAS1PTGES2CYP11B1CYP11B2MAOA | |
| SCHEMBL28107225 | 0.78 | CYP11B2 (0.50) | TBXAS1PTGES2CYP11B1CYP11B2MAOA | |
| SCHEMBL1606344 | 0.78 | TBXAS1 (0.52) | TBXAS1PTGES2CYP11B1CYP11B2MAOA | |
| SCHEMBL1606190 | 0.77 | DRD2 (0.51) | TBXAS1PTGES2CYP11B1CYP11B2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104193725-B | Organic compound | 诺华股份有限公司 | 2016-11-16 | — | — | CN | disclosed |