Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.56 |
| ▸ | CDC7 | O00311 | 6/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 3/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6654549 | 0.87 | CYP11B2 (0.53) | CYP19A1CDC7CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL6663716 | 0.83 | CYP11B2 (0.49) | CYP19A1CDC7CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL4282844 | 0.83 | ENPP3 (0.56) | CYP19A1CDC7ENPP3CDK2FFAR4 | |
| SCHEMBL6844281 | 0.82 | CYP11B2 (0.57) | CYP19A1CDC7CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL15742146 | 0.81 | CDC7 (0.51) | CYP19A1CDC7CYP11B2PTGER2ENPP3 | |
| SCHEMBL3927305 | 0.80 | PTGER2 (0.42) | CYP19A1CDC7CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL6658847 | 0.80 | BRPF1 (0.60) | CYP19A1 | |
| SCHEMBL28562388 | 0.78 | CDC7 (0.60) | CYP19A1CDC7CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL17067754 | 0.78 | ROCK1 (0.50) | CYP19A1CYP11B2CYP11B1 | |
| SCHEMBL8306084 | 0.78 | CYP19A1 (0.53) | CYP19A1CYP11B2CYP11B1PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104193725-B | Organic compound | 诺华股份有限公司 | 2016-11-16 | — | — | CN | disclosed |