Pyrrole

Pyrrole

SCHEMBL28107126

O=S(=O)(O)c1cccnc1S(=O)(=O)O.c1cc[nH]c1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
COMT P21964 2/20 0.41
ALDH1A1 P00352 3/20 0.40
CYP1A2 P05177 2/20 0.40
HIF1A Q16665 2/20 0.40
ALOX15 P16050 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MEN1 O00255 1/20 0.36
NSD2 O96028 1/20 0.36
POLB P06746 1/20 0.36
IDE P14735 1/20 0.36
DUSP3 P51452 1/20 0.36
CCR6 P51684 1/20 0.36
BLM P54132 1/20 0.36
KMT2A Q03164 1/20 0.36
NAPRT Q6XQN6 1/20 0.34
KDM4E B2RXH2 5/20 0.34
MAPK1 P28482 2/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2112972 0.89 COMT (0.49) COMTALDH1A1CYP1A2HIF1AALOX15
SCHEMBL29564068 0.89 COMT (0.49) COMTALDH1A1CYP1A2HIF1AALOX15
Hydrochloric Acid SCHEMBL28205807 0.76 COMT (0.50) COMTALDH1A1CYP1A2HIF1AALOX15
SCHEMBL4660499 0.71 COMT (0.50) COMTALDH1A1CYP1A2HIF1AALOX15
SCHEMBL7867326 0.70 COMT (0.53) COMTALDH1A1CYP1A2HIF1AALOX15
SCHEMBL9002773 0.70 COMT (0.49) COMTALDH1A1CYP1A2HIF1AALOX15
SCHEMBL28502273 0.70 NFE2L2 (0.43) COMTNAPRTKDM4EALOX12HTT
SCHEMBL7081072 0.70 KDM4E (0.53) COMTALDH1A1CYP1A2HIF1AALOX15
Pyrrole SCHEMBL28855331 0.69 MYC (0.44) ALDH1A1MEN1POLBKMT2AKDM4E
SCHEMBL3717899 0.69 COMT (0.41) COMTALDH1A1CYP1A2HIF1AALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106029740-B For improving the additive of the rheological characteristic of inorganic adhesive 建筑研究和技术有限公司 2018-12-25 CN disclosed
CN-108699233-A Water-reducing agent based on condensation polymer 建筑研究和技术有限公司 2018-10-23 CN disclosed
CN-106029740-A Additive for rheology improvement of inorganic binders 建筑研究和技术有限公司 2016-10-12 CN disclosed