Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445164 | 0.80 | GRM5 (0.40) | COMTKDM4ELMNAL3MBTL1HTT | |
| SCHEMBL28189822 | 0.79 | LIMK2 (0.46) | KDM4ELMNAL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL27866602 | 0.79 | KDM4E (0.41) | COMTKDM4ELMNAL3MBTL1HTT | |
| Hydrochloric Acid SCHEMBL27769855 | 0.78 | KDM4E (0.40) | COMTKDM4ELMNAL3MBTL1GAA | |
| Sulfuric Acid SCHEMBL28693835 | 0.76 | TSHR (0.37) | COMTKDM4ELMNAL3MBTL1HTT | |
| SCHEMBL27807031 | 0.75 | LIPG (0.45) | L3MBTL1TDP1 | |
| SCHEMBL27807092 | 0.75 | LIPG (0.45) | L3MBTL1TDP1 | |
| SCHEMBL2112972 | 0.74 | COMT (0.49) | COMTKDM4ELMNAL3MBTL1HTT | |
| SCHEMBL29564068 | 0.74 | COMT (0.49) | COMTKDM4ELMNAL3MBTL1HTT | |
| SCHEMBL7081072 | 0.74 | KDM4E (0.53) | COMTKDM4ELMNAL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142934-A1 | INDOLE DERIVATIVES AS LIGANDS OF CRTH2 RECEPTORS | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |