Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1995318 | 0.90 | THRB (0.48) | THRBLMNAGAANOTUMTAS2R14 | |
| SCHEMBL3374645 | 0.83 | TAS2R14 (0.46) | SMN1; SMN2LMNAGAATAS2R14L3MBTL1 | |
| SCHEMBL11846322 | 0.80 | THRB (0.54) | SMN1; SMN2THRBLMNAGAAMAOB | |
| SCHEMBL23364641 | 0.79 | THRB (0.42) | THRBLMNAGAANOTUMTAS2R14 | |
| SCHEMBL29932939 | 0.79 | THRB (0.42) | THRBLMNAGAANOTUMTAS2R14 | |
| SCHEMBL30313345 | 0.79 | CES2 (0.48) | THRBNOTUMMAOAMAOBRORC | |
| SCHEMBL13519060 | 0.79 | THRB (0.63) | THRBLMNAGAANOTUMMAOA | |
| SCHEMBL716995 | 0.79 | CES2 (0.48) | THRBNOTUMMAOAMAOBRORC | |
| SCHEMBL29932942 | 0.78 | TYK2 (0.54) | SMN1; SMN2THRBTYK2RORC | |
| SCHEMBL9525419 | 0.78 | TYK2 (0.54) | SMN1; SMN2THRBTYK2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103936819-B | Hepatitis c virus inhibitors | 百时美施贵宝公司 | 2016-11-16 | — | — | CN | disclosed |