Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimethyl Sulfoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195751 | 0.90 | ALDH1A1 (0.54) | NAAAALDH1A1ATMDGKATSHR | |
| SCHEMBL3205502 | 0.84 | NAAA (0.63) | NAAAALDH1A1DGKATSHRRAD52 | |
| SCHEMBL31509134 | 0.82 | NAAA (0.67) | NAAAALDH1A1DGKATSHRRAD52 | |
| SCHEMBL7640502 | 0.82 | NAAA (0.67) | NAAAALDH1A1DGKATSHRRAD52 | |
| SCHEMBL16213825 | 0.82 | NAAA (0.67) | NAAAALDH1A1DGKATSHRRAD52 | |
| SCHEMBL8008281 | 0.82 | NAAA (0.67) | NAAAALDH1A1DGKATSHRRAD52 | |
| Acetic Acid Butyl Ester SCHEMBL4832766 | 0.80 | ALDH1A1 (0.64) | NAAAALDH1A1ATMDGKATSHR | |
| SCHEMBL12287446 | 0.80 | NAAA (0.48) | NAAAALDH1A1DGKATSHRRAD52 | |
| SCHEMBL29075 | 0.78 | — | — | |
| SCHEMBL17582700 | 0.77 | NAAA (0.42) | NAAAALDH1A1ATMDGKATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106103612-B | Fluoro-containing coating composition and article | ＡＧＣ株式会社 | 2018-11-30 | — | — | CN | disclosed |
| CN-106103612-A | Fluoro-containing coating compositions and article | 旭硝子株式会社 | 2016-11-09 | — | — | CN | disclosed |