Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | WEE1 | P30291 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22544312 | 0.91 | HSD17B10 (0.53) | HSD17B10RXRARXRBGPR3KDM4E | |
| SCHEMBL28107672 | 0.86 | HSD17B10 (0.46) | HSD17B10RXRARXRBGPR3ALDH1A1 | |
| SCHEMBL28107676 | 0.86 | HSD17B10 (0.46) | HSD17B10BCHEACHERXRARXRB | |
| SCHEMBL28107376 | 0.84 | L3MBTL1 (0.51) | HSD17B10BCHEACHEKDM4EALDH1A1 | |
| SCHEMBL28107373 | 0.83 | CYP2A6 (0.47) | HSD17B10RXRARXRBGPR3KDM4E | |
| SCHEMBL28107380 | 0.83 | CHEK1 (0.41) | HSD17B10KDM4EALDH1A1POLBHTT | |
| SCHEMBL28107677 | 0.82 | HSD17B10 (0.44) | HSD17B10RXRARXRBGPR3KDM4E | |
| SCHEMBL28835460 | 0.81 | AURKA (0.51) | HSD17B10KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL27012188 | 0.80 | CYP1A2 (0.39) | CYP1A2KDM4EALDH1A1POLBHTT | |
| SCHEMBL28319588 | 0.78 | HSD17B10 (0.46) | HSD17B10GPR3ALDH1A1KMT2ACHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117113-B | Polysubstituted carbazole, derivative and its synthetic method | 湘潭大学 | 2019-08-16 | — | — | CN | disclosed |
| CN-106117113-A | Polysubstituted carbazole, derivant and synthetic method thereof | 湘潭大学 | 2016-11-16 | — | — | CN | disclosed |