Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22544312 | 0.91 | HSD17B10 (0.53) | HSD17B10RXRARXRBGPR3HPGD | |
| SCHEMBL28107378 | 0.86 | HSD17B10 (0.46) | HSD17B10RXRARXRBGPR3HPGD | |
| SCHEMBL28107676 | 0.86 | HSD17B10 (0.46) | HSD17B10RXRARXRBGPR3NPSR1 | |
| SCHEMBL28107376 | 0.84 | L3MBTL1 (0.51) | HSD17B10NPSR1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL28107677 | 0.82 | HSD17B10 (0.44) | HSD17B10RXRARXRBGPR3HPGD | |
| SCHEMBL28107373 | 0.78 | CYP2A6 (0.47) | HSD17B10RXRARXRBGPR3MAPK14 | |
| SCHEMBL28319588 | 0.78 | HSD17B10 (0.46) | HSD17B10GPR3HPGDKMT2AALDH1A1 | |
| SCHEMBL28107372 | 0.77 | HSD17B10 (0.43) | HSD17B10RXRARXRBGPR3HPGD | |
| SCHEMBL28107427 | 0.76 | HSD17B10 (0.43) | HSD17B10ATMGPR3MAPK14NPSR1 | |
| SCHEMBL22499353 | 0.75 | GPR3 (0.47) | HSD17B10ATMRXRARXRBGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117113-B | Polysubstituted carbazole, derivative and its synthetic method | 湘潭大学 | 2019-08-16 | — | — | CN | disclosed |
| CN-106117113-A | Polysubstituted carbazole, derivant and synthetic method thereof | 湘潭大学 | 2016-11-16 | — | — | CN | disclosed |