Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | WEE1 | P30291 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22544312 | 0.85 | HSD17B10 (0.53) | HSD17B10GPR3CHEK1WEE1HPGD | |
| SCHEMBL28319588 | 0.83 | HSD17B10 (0.46) | HSD11B1HSD17B10GPR3CHEK1WEE1 | |
| SCHEMBL28107378 | 0.83 | HSD17B10 (0.46) | HSD11B1HSD17B10GPR3CHEK1WEE1 | |
| SCHEMBL28107672 | 0.78 | HSD17B10 (0.46) | HSD17B10GPR3MAPK14CHEK1WEE1 | |
| SCHEMBL28107676 | 0.78 | HSD17B10 (0.46) | HSD17B10GPR3CHEK1WEE1HPGD | |
| SCHEMBL883708 | 0.77 | GPR3 (0.54) | HSD11B1HSD17B10GPR3HPGDALDH1A1 | |
| SCHEMBL28107677 | 0.77 | HSD17B10 (0.44) | HSD17B10GPR3CHEK1WEE1HPGD | |
| SCHEMBL28107376 | 0.76 | L3MBTL1 (0.51) | HSD17B10HPGDALDH1A1KDM4EMAPT | |
| SCHEMBL28107427 | 0.76 | HSD17B10 (0.43) | HSD17B10GPR3MAPK14HPGDALDH1A1 | |
| SCHEMBL28107372 | 0.75 | HSD17B10 (0.43) | HSD17B10GPR3HPGDALDH1A1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117113-B | Polysubstituted carbazole, derivative and its synthetic method | 湘潭大学 | 2019-08-16 | — | — | CN | disclosed |
| CN-106117113-A | Polysubstituted carbazole, derivant and synthetic method thereof | 湘潭大学 | 2016-11-16 | — | — | CN | disclosed |