Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15124839 | 0.78 | MAOA (0.82) | MAOAMAOBALDH1A1GAAKDM4E | |
| SCHEMBL27889436 | 0.78 | MAOA (1.00) | MAOAMAOBALDH1A1GAAKDM4E | |
| SCHEMBL455949 | 0.78 | MAOA (1.00) | MAOAMAOBALDH1A1GAAKDM4E | |
| SCHEMBL9593514 | 0.77 | MAOA (0.67) | MAOAMAOBALDH1A1GAAKDM4E | |
| SCHEMBL9709249 | 0.77 | MAOA (0.72) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL29566948 | 0.76 | MAOA (0.55) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL4371752 | 0.76 | NQO2 (0.54) | KIF11ALDH1A1KDM4EHPGDCYP1A2 | |
| Hydrochloric Acid SCHEMBL28400797 | 0.75 | MAOA (0.95) | MAOAMAOBALDH1A1GAAKDM4E | |
| SCHEMBL13071394 | 0.75 | ADORA1 (0.51) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL28107454 | 0.75 | MAOA (0.53) | MAOAMAOBALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045973-B | 4- amide groups benzimidazole acridine compound and its preparation method and application | 清华大学深圳研究生院 | 2019-03-22 | — | — | CN | disclosed |
| CN-106045973-A | 4-Amidobenzoimidazolacridine compound and preparation method and application thereof | 清华大学深圳研究生院 | 2016-10-26 | — | — | CN | disclosed |