Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073871 | 0.79 | PSMB5 (0.54) | PSMB5DHODHKDM4EALDH1A1GAA | |
| SCHEMBL840409 | 0.77 | TLR8 (0.51) | PSMB5TLR7TLR8 | |
| SCHEMBL27961875 | 0.75 | TLR8 (0.55) | MAOAMAOBPSMB5KDM4EALDH1A1 | |
| SCHEMBL28107456 | 0.75 | MAOA (0.60) | MAOAMAOBKDM4EALDH1A1GAA | |
| SCHEMBL29488276 | 0.74 | DHODH (0.58) | PSMB5DHODHKDM4EALDH1A1GAA | |
| SCHEMBL17423277 | 0.74 | KDM4E (0.59) | PSMB5DHODHKDM4EALDH1A1GAA | |
| SCHEMBL601489 | 0.74 | DHODH (0.58) | PSMB5DHODHKDM4EALDH1A1GAA | |
| SCHEMBL29587930 | 0.73 | PSMB5 (0.49) | PSMB5DHODHKDM4EALDH1A1GAA | |
| SCHEMBL600671 | 0.73 | PSMB5 (0.49) | PSMB5DHODHKDM4EALDH1A1GAA | |
| Phenazine SCHEMBL28800562 | 0.73 | KDM4E (0.52) | PSMB5DHODHKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045973-B | 4- amide groups benzimidazole acridine compound and its preparation method and application | 清华大学深圳研究生院 | 2019-03-22 | — | — | CN | disclosed |
| CN-106045973-A | 4-Amidobenzoimidazolacridine compound and preparation method and application thereof | 清华大学深圳研究生院 | 2016-10-26 | — | — | CN | disclosed |