Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | FADS1 | O60427 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20414976 | 0.91 | ALDH1A1 (0.41) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL1007069 | 0.86 | MAPT (0.39) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| Bromide SCHEMBL30903858 | 0.84 | MAPT (0.38) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1156365 | 0.84 | SMN1; SMN2 (0.41) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL28424843 | 0.82 | MAPT (0.34) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL5577143 | 0.78 | FAAH (0.34) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL28402413 | 0.77 | ALDH1A1 (0.49) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL16429033 | 0.76 | MAPT (0.50) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| Acetic Acid SCHEMBL28557579 | 0.74 | NOTUM (0.40) | ALDH1A1LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL19277406 | 0.74 | TSHR (0.48) | ALDH1A1HPGDLMNANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103596957-B | Imidazopyridazines as AKT kinase inhibitors | 拜耳知识产权有限责任公司 | 2016-12-07 | — | — | CN | disclosed |