Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PON1 | P27169 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27953149 | 0.76 | PON1 (0.32) | PON1KMT2ANPSR1 | |
| SCHEMBL13584746 | 0.74 | SHBG (0.35) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| SCHEMBL29168488 | 0.73 | GABRA1 (0.30) | — | |
| SCHEMBL11836795 | 0.72 | KMT2A (0.38) | PON1ALDH1A1HIF1AKMT2ANPSR1 | |
| SCHEMBL3403920 | 0.69 | KMT2A (0.33) | ALDH1A1KMT2ANPSR1 | |
| SCHEMBL1336683 | 0.69 | PGK1 (0.42) | PON1ALDH1A1HIF1AHSD17B10KMT2A | |
| SCHEMBL128934 | 0.69 | PON1 (0.40) | PON1 | |
| SCHEMBL10890673 | 0.68 | PON1 (0.35) | PON1ALDH1A1CYP1A2ALOX15CASP7 | |
| SCHEMBL15890143 | 0.67 | TSHR (0.36) | PON1ALDH1A1CYP1A2ALOX15CASP7 | |
| SCHEMBL3824444 | 0.67 | KDM4E (0.43) | PON1ALDH1A1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722656-B2 | Cephalosporins useful as antibacterial agents | ZOETIS LLC (US) | 2014-05-13 | — | — | US | disclosed |
| EP-2705044-A1 | NOVEL CEPHALOSPORINS USEFUL AS ANTIBACTERIAL AGENTS | ZOETIS LLC (US) | 2014-03-12 | — | — | EP | disclosed |
| WO-2012150520-A1 | NOVEL CEPHALOSPORINS USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2012-11-08 | — | — | WO | disclosed |
| US-20120283237-A1 | NOVEL CEPHALOSPORINS USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2012-11-08 | — | — | US | disclosed |
| US-20100240713-A1 | AROMATIC AND HETEROAROMATIC COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2010-09-23 | — | — | US | disclosed |
| EP-2068855-A2 | AROMATIC AND HETEROAROMATIC COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008151288-A2 | AROMATIC AND HETEROAROMATIC COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283237-A1 | NOVEL CEPHALOSPORINS USEFUL AS ANTIBACTERIAL AGENTS | CIAPIN1, CLSPN, MRPL21 | PON1 1426/4885ALDH1A1 3155/4885CYP1A2 593/4885 |
| US-20100240713-A1 | AROMATIC AND HETEROAROMATIC COMPOUNDS USEFUL IN TREATING IRON DISORDERS | SLC40A1, PAH, FECH | PON1 953/4885ALDH1A1 749/4885CYP1A2 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.