Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 7/20 | 0.36 |
| ▸ | METAP1 | P53582 | 5/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234751 | 0.84 | ALDH1A1 (0.46) | ALOX15CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8738949 | 0.78 | ALDH1A1 (0.40) | ALOX15CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL1227849 | 0.78 | ALDH1A1 (0.40) | ALOX15CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL14764283 | 0.78 | MGAM (0.38) | ALOX15ALDH1A1POLBMETAP2METAP1 | |
| SCHEMBL4755464 | 0.77 | TDP1 (0.44) | ALOX15ALDH1A1POLBLMNAHSD17B10 | |
| SCHEMBL4755469 | 0.77 | TDP1 (0.44) | ALOX15ALDH1A1POLBLMNAHSD17B10 | |
| SCHEMBL15015759 | 0.77 | TDP1 (0.44) | ALOX15ALDH1A1POLBLMNAHSD17B10 | |
| SCHEMBL18050528 | 0.76 | CA2 (0.40) | ALDH1A1POLBCPB2TDP1 | |
| SCHEMBL14764285 | 0.76 | POLB (0.35) | ALOX15CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL3195561 | 0.76 | ALOX15 (0.44) | ALOX15CYP2D6CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105992763-A | Neprilysin inhibitors | 施万生物制药研发IP有限责任公司 | 2016-10-05 | — | — | CN | disclosed |