Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | ALPG | P10696 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | THRA | P10827 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6402196 | 0.95 | MAPT (0.60) | MAPTLMNANPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11407762 | 0.92 | PRSS1 (0.61) | MAPTLMNANPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8424596 | 0.91 | MAPT (0.60) | MAPTLMNANPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11407781 | 0.89 | PRSS1 (0.57) | MAPTLMNANPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11408494 | 0.88 | RECQL (0.58) | MAPTLMNANPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4313215 | 0.84 | LMNA (0.58) | MAPTLMNASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL11874767 | 0.84 | ALDH1A1 (0.52) | MAPTLMNASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8973693 | 0.84 | CYP19A1 (0.57) | MAPTLMNANPSR1SMN1; SMN2ALDH1A1 | |
| Methane SCHEMBL27705473 | 0.83 | LMNA (0.56) | MAPTLMNASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL11572440 | 0.82 | CYP19A1 (0.60) | MAPTLMNANPSR1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146419-A | Xanthine oxidase inhibitor | 沈阳药科大学 | 2016-11-23 | — | — | CN | disclosed |