Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ALPG | P10696 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28108809 | 0.95 | MAPT (0.61) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8424596 | 0.92 | MAPT (0.60) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11407762 | 0.91 | PRSS1 (0.61) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11407781 | 0.91 | PRSS1 (0.57) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11408494 | 0.89 | RECQL (0.58) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4313215 | 0.86 | LMNA (0.58) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11874767 | 0.85 | ALDH1A1 (0.52) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Methane SCHEMBL27705473 | 0.84 | LMNA (0.56) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11136715 | 0.83 | PRSS1 (0.54) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8973683 | 0.83 | ALDH1A1 (0.56) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106673935-A | Dimerization method of 1-butylene | 中国石油化工股份有限公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-106673942-A | 1-butene dimerization method | 中国石油化工股份有限公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-106673934-A | Dimerization method for 1-butene | 中国石油化工股份有限公司 | 2017-05-17 | — | — | CN | disclosed |
| US-20050054629-A1 | Compounds and methods of treating cell proliferative diseases | EXONHIT THERAPEUTICS SA (FR) | 2005-03-10 | — | — | US | disclosed |
| EP-1480966-A1 | COMPOUNDS AND METHODS OF TREATING CELL PROLIFERATIVE DISEASES | Exonhit Therapeutics S.A. (FR) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074508-A1 | COMPOUNDS AND METHODS OF TREATING CELL PROLIFERATIVE DISEASES | EXONHIT THERAPEUTICS SA (FR) | 2003-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054629-A1 | Compounds and methods of treating cell proliferative diseases | MKI67, CCNC, PCNA | MAPT 2267/4885ALDH1A1 867/4885NPC1 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.