Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28108882 | 0.78 | — | — | |
| SCHEMBL28018377 | 0.77 | PIN1 (0.40) | MAPTLMNANPC1RAB9APIN1 | |
| SCHEMBL10265983 | 0.76 | GPR35 (0.35) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL16564138 | 0.70 | MAPT (0.44) | MAPTALDH1A1LMNANPC1RAB9A | |
| SCHEMBL8562235 | 0.70 | TDP1 (0.48) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL27770905 | 0.70 | HDAC1 (0.31) | LMNAPOLB | |
| SCHEMBL28874590 | 0.67 | PDE7A (0.37) | MAPTALDH1A1LMNANPC1RAB9A | |
| SCHEMBL7005138 | 0.67 | CYP19A1 (0.45) | ALDH1A1LMNAPOLBCYP3A4TSHR | |
| SCHEMBL711811 | 0.67 | MAPT (0.37) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL899057 | 0.67 | MAPT (0.41) | MAPTALDH1A1TDP1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459060-B | Condensed triazole derivative as phosphodiesterase 10 A inhibitor | 赛隆制药股份公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-106459060-A | Fused triazole derivatives as phosphodiesterase 10A inhibitors | 赛隆制药股份公司 | 2017-02-22 | — | — | CN | disclosed |