Benzophenone

Benzophenone

SCHEMBL28109342

CC(=O)Cc1ccncc1.O=C(c1ccccc1)c1ccccc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.63
MEN1 O00255 1/20 0.63
NPY5R Q15761 2/20 0.51
CYP19A1 P11511 2/20 0.50
ALDH1A1 P00352 3/20 0.49
GAA P10253 2/20 0.49
MAPT P10636 2/20 0.49
PLOD2 O00469 1/20 0.49
PLOD3 O60568 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
HPGD P15428 1/20 0.49
CYP2C19 P33261 1/20 0.49
PLOD1 Q02809 1/20 0.49
HIF1A Q16665 1/20 0.49
MAPK7 Q13164 1/20 0.47
FNTA P49354 1/20 0.47
FNTB P49356 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16162416 0.85 ALDH1A1 (0.56) KMT2AMEN1ALDH1A1GAAMAPT
SCHEMBL48403 0.85 CYP19A1 (0.50) CYP19A1ALDH1A1GAAMAPT
Iodide SCHEMBL14765165 0.83 CYP19A1 (0.49) CYP19A1ALDH1A1GAAMAPT
SCHEMBL229650 0.79 KMT2A (1.00) KMT2AMEN1NPY5RALDH1A1PLOD2
SCHEMBL1157353 0.78 ALDH1A1 (0.66) KMT2AMEN1CYP19A1ALDH1A1GAA
SCHEMBL10727829 0.77 L3MBTL1 (0.59) CYP19A1ALDH1A1MAPTCYP3A4HPGD
SCHEMBL10775090 0.77 POLB (0.52) KMT2AALDH1A1MAPTHPGDSRD5A2
Benzene SCHEMBL2333780 0.77 CES1 (0.64) KMT2AMEN1ALDH1A1GAAFNTA
Benzene SCHEMBL7058395 0.77 CES1 (0.64) KMT2AMEN1ALDH1A1GAAFNTA
SCHEMBL1331954 0.77 CES1 (0.64) KMT2AMEN1ALDH1A1GAAFNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106232771-B The new chromophore architectures of lanthanide chelate 雷度米特图尔库公司 2019-04-30 CN disclosed
CN-106232771-A The new chromophore architectures in the lanthanide chelate field of the present invention 雷度米特图尔库公司 2016-12-14 CN disclosed