Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL14765165 | 0.98 | CYP19A1 (0.49) | CYP19A1TSHRALDH1A1GAAMAPT | |
| SCHEMBL8081061 | 0.90 | ALDH1A1 (0.47) | CYP19A1TSHRALDH1A1GAAMAPT | |
| SCHEMBL28163187 | 0.90 | GAA (0.54) | CYP19A1TSHRALDH1A1GAAMAPT | |
| Benzophenone SCHEMBL28109342 | 0.85 | KMT2A (0.63) | CYP19A1ALDH1A1GAAMAPT | |
| SCHEMBL16866569 | 0.82 | POLB (0.54) | CYP19A1ALDH1A1MAPTPOLBRAB9A | |
| SCHEMBL9630186 | 0.82 | MAOB (0.53) | ALDH1A1MAPTPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL9632286 | 0.82 | MAOB (0.53) | ALDH1A1MAPTPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL8403545 | 0.82 | POLB (0.61) | TSHRALDH1A1GAAPOLBHTT | |
| SCHEMBL4681053 | 0.80 | LOXL2 (0.46) | CYP19A1TSHRALDH1A1GAAMAPT | |
| SCHEMBL10750108 | 0.80 | CYP19A1 (0.52) | CYP19A1ALDH1A1GAAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111377857-B | Method for synthesizing milrinone | 鲁南制药集团股份有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-111377858-B | Preparation method of milrinone | 鲁南制药集团股份有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-113493411-A | Method for synthesizing milrinone | 鲁南制药集团股份有限公司 | 2021-10-12 | — | — | CN | claimed |
| CN-109562628-B | Silver ion carboxylate N-heteroaromatic complex and use | 柯达公司 | 2021-07-27 | — | — | CN | claimed |
| EP-3496951-B1 | SILVER ION CARBOXYLATE N-HETEROAROMATIC COMPLEXES AND USES | EASTMAN KODAK CO (US) | 2021-06-23 | — | — | EP | claimed |
| CN-111484450-A | Preparation method of medical intermediate milrinone | 上海隆盛化工有限公司 | 2020-08-04 | — | — | CN | claimed |
| US-20190264331-A1 | COMPOSITIONS AND METHODS FOR FORMING ARTICLES HAVING SILVER METAL | BANK OF AMERICA, N.A., AS AGENT | 2019-08-29 | — | — | US | claimed |
| US-10358725-B2 | Compositions and methods for forming articles having silver metal | EASTMAN KODAK COMPANY (US) | 2019-07-23 | — | — | US | claimed |
| US-10356899-B2 | Articles having reducible silver ion complexes or silver metal | EASTMAN KODAK COMPANY (US) | 2019-07-16 | — | — | US | claimed |
| EP-3496951-A1 | SILVER ION CARBOXYLATE N-HETEROAROMATIC COMPLEXES AND USES | Eastman Kodak Company (US) | 2019-06-19 | — | — | EP | claimed |
| CN-1253439-C | Process for preparing milrinone | LUNAN PHARM GROUP CORP (CN) | 2006-04-26 | — | — | CN | claimed |
| CN-1629141-A | Process for preparing milrinone | LUNAN PHARM GROUP CORP (CN) | 2005-06-22 | — | — | CN | claimed |
| EP-0159769-B1 | ELECTROCHEMICAL OXIDATION OF PYRIDINE BASES | REILLY INDUSTRIES, INC. (US) | 1991-03-27 | — | — | EP | claimed |
| EP-0159769-A1 | Electrochemical oxidation of pyridine bases | REILLY INDUSTRIES, INC. (US) | 1985-10-30 | — | — | EP | claimed |
| EP-0075116-B1 | PROCESS FOR PREPARING 1,2-DIHYDRO-6-METHYL-2-OXO-5-(PYRIDINYL)NICOTINONITRILES | STERLING DRUG INC. (US) | 1985-05-22 | — | — | EP | claimed |
| US-4482439-A | Electrochemical oxidation of pyridine bases | REILLY TAR & CHEMICAL CORP. (US) | 1984-11-13 | — | — | US | claimed |
| US-4469871-A | Process for preparing 2-(lower-alkoxy)-1-(pyridinyl) ethenyl lower-alkyl ketones | STERLING DRUG INC. (US) | 1984-09-04 | — | — | US | claimed |
| US-4413127-A | Preparation of 1,2-dihydro-6-(lower alkyl)-2-oxo-5-(pyridinyl)nicotinonitriles | STERLING DRUG INC. (US) | 1983-11-01 | — | — | US | claimed |
| EP-0075116-A1 | Process for preparing 1,2-dihydro-6-methyl-2-oxo-5-(pyridinyl)nicotinonitriles | STERLING DRUG INC. (US) | 1983-03-30 | — | — | EP | claimed |
| US-4347363-A | Process for preparing 1,2-dihydro-6-methyl-2-oxo-5-(pyridinyl)nicotinonitriles | STERLING DRUG INC. (US) | 1982-08-31 | — | — | US | claimed |