Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | CBR1 | P16152 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.57 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.57 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27582898 | 0.87 | LMNA (0.67) | SMN1; SMN2LMNAHTTNPC1TP53 | |
| SCHEMBL7820305 | 0.84 | SMN1; SMN2 (0.70) | SMN1; SMN2GAAKDM4EALDH1A1KMT2A | |
| SCHEMBL3279232 | 0.84 | TMPRSS4 (0.70) | SMN1; SMN2LMNAHTTNPC1TP53 | |
| SCHEMBL30771738 | 0.83 | TMPRSS4 (0.73) | SMN1; SMN2KDM4EP2RX1P2RX4P2RX7 | |
| SCHEMBL329995 | 0.83 | TMPRSS4 (0.73) | SMN1; SMN2KDM4EP2RX1P2RX4P2RX7 | |
| SCHEMBL28636438 | 0.83 | KDM4E (0.74) | SMN1; SMN2HTTGAAKDM4EALDH1A1 | |
| SCHEMBL7678596 | 0.82 | LMNA (0.88) | SMN1; SMN2LMNAHTTNPC1TP53 | |
| SCHEMBL11036423 | 0.82 | CBR1 (0.65) | SMN1; SMN2LMNAHTTNPC1GAA | |
| SCHEMBL34475650 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTNPC1TP53 | |
| SCHEMBL845142 | 0.81 | LMNA (1.00) | SMN1; SMN2LMNAHTTNPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106456461-A | Oral care composition containing silica and zinc citrate | 高露洁-棕榄公司 | 2017-02-22 | — | — | CN | claimed |