SCHEMBL281104

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL281432	0.91	SIRT1 (0.46)	GSK3BMAPTSCN9AMAPK10HIF1A
	SCHEMBL281584	0.84	SIRT1 (0.47)	GSK3BMAPTL3MBTL1SCN9AMAPK10
	SCHEMBL27728430	0.81	SCN9A (0.46)	GSK3BSCN9AGAAMEN1KMT2A
	SCHEMBL12470372	0.79	GSK3B (0.54)	GSK3BMAPTSCN9AGAAKMT2A
	SCHEMBL2994860	0.77	SCN9A (0.52)	GSK3BSCN9AGAAKMT2ATSHR
	SCHEMBL27707812	0.76	SCN9A (0.54)	SCN9AGAATSHRALDH1A1LMNA
	SCHEMBL281753	0.76	SCN9A (0.55)	GSK3BMAPTSCN9AGAAMEN1
	SCHEMBL27707819	0.76	SCN9A (0.53)	GSK3BMAPTSCN9AGAATHRB
	SCHEMBL19763099	0.76	SCN9A (0.48)	GSK3BSCN9AGAAKMT2ATSHR
	SCHEMBL14506502	0.76	SCN9A (0.51)	MAPTSCN9AGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.