SCHEMBL28110441

SCHEMBL28110441

NC(=O)CC(=O)COCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.50
RAB9A P51151 2/20 0.50
TSHR P16473 1/20 0.48
TP53 P04637 1/20 0.44
MAPT P10636 1/20 0.44
GRM5 P41594 1/20 0.44
HTT P42858 1/20 0.44
PARP10 Q53GL7 1/20 0.44
ALDH1A1 P00352 2/20 0.43
SLC1A1 P43005 1/20 0.43
CSNK1D P48730 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6702666 0.89 TSHR (0.56) NPC1RAB9ATSHRMAPTGRM5
SCHEMBL1987313 0.85 TSHR (0.52) NPC1RAB9ATSHRMAPTGRM5
SCHEMBL203767 0.85 TSHR (0.56) NPC1RAB9ATSHRTP53MAPT
SCHEMBL476827 0.85 TSHR (0.61) NPC1RAB9ATSHRMAPTGRM5
SCHEMBL3986734 0.82 NPC1 (0.49) NPC1RAB9ATSHRMAPTGRM5
SCHEMBL9622282 0.82 NPC1 (0.52) NPC1RAB9ATSHRMAPTGRM5
SCHEMBL29153306 0.82 ALDH1A1 (0.52) NPC1RAB9ATSHRMAPTGRM5
Formaldehyde SCHEMBL8658362 0.81 TSHR (0.56) NPC1RAB9ATSHRMAPTGRM5
SCHEMBL9152703 0.81 NPC1 (0.51) NPC1RAB9ATSHRMAPTGRM5
SCHEMBL126148 0.81 NPC1 (0.55) NPC1RAB9ATSHRMAPTGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104053727-B Thiophene azo carboxylate's dyestuff and comprise its fabric care composition MILLIKEN & CO. (US) 2016-11-30 CN disclosed