Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 3/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702666 | 0.89 | TSHR (0.56) | ALDH1A1NPC1TSHRRAB9AGRM5 | |
| SCHEMBL1987313 | 0.85 | TSHR (0.52) | ALDH1A1NPC1TSHRRAB9AGRM5 | |
| SCHEMBL73270 | 0.85 | ALDH1A1 (0.59) | ALDH1A1NPC1TSHRRAB9AGRM5 | |
| SCHEMBL476827 | 0.85 | TSHR (0.61) | ALDH1A1NPC1TSHRRAB9AGRM5 | |
| SCHEMBL3986734 | 0.82 | NPC1 (0.49) | ALDH1A1NPC1TSHRRAB9AGRM5 | |
| SCHEMBL28110441 | 0.82 | NPC1 (0.50) | ALDH1A1NPC1TSHRRAB9AGRM5 | |
| SCHEMBL9622282 | 0.82 | NPC1 (0.52) | ALDH1A1NPC1TSHRRAB9AGRM5 | |
| SCHEMBL6905812 | 0.81 | TSHR (0.52) | ALDH1A1NPC1TSHRRAB9AGRM5 | |
| Formaldehyde SCHEMBL8658362 | 0.81 | TSHR (0.56) | ALDH1A1NPC1TSHRRAB9AGRM5 | |
| SCHEMBL126148 | 0.81 | NPC1 (0.55) | ALDH1A1NPC1TSHRRAB9AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003747-A | Compound for inhibiting FGFR4 kinase and application thereof | 察略盛医药科技(上海)有限公司 | 2023-11-07 | — | — | CN | disclosed |