SCHEMBL28110490

SCHEMBL28110490

C=Cc1ccc(C(O)CCO)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
RIPK1 Q13546 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.37
TAS1R1 Q7RTX1 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
TSHR P16473 2/20 0.36
HDAC8 Q9BY41 1/20 0.35
TAAR1 Q96RJ0 2/20 0.33
HTR3A P46098 1/20 0.33
NFKB1 P19838 1/20 0.33
HIF1A Q16665 1/20 0.33
PLAU P00749 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ALOX15 P16050 1/20 0.32
APEX1 P27695 1/20 0.32
AOC3 Q16853 1/20 0.32
DRD4 P21917 3/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27555588 0.90 ALDH1A1 (0.44) ALDH1A1RIPK1TAS1R3TAS1R1TDP1
SCHEMBL5681566 0.83 ALDH1A1 (0.50) ALDH1A1TAS1R3TAS1R1TDP1TSHR
SCHEMBL5133124 0.82 TAS1R3 (0.50) ALDH1A1RIPK1TAS1R3TAS1R1TDP1
SCHEMBL1901260 0.80 ALDH1A1 (0.42) ALDH1A1TAS1R3TAS1R1TDP1TSHR
SCHEMBL4237262 0.80 TAS1R3 (0.45) ALDH1A1RIPK1TAS1R3TAS1R1TDP1
SCHEMBL5203081 0.80 ALDH1A1 (0.42) ALDH1A1RIPK1TAS1R3TAS1R1TDP1
SCHEMBL11982047 0.79 TAS1R3 (0.44) ALDH1A1RIPK1TAS1R3TAS1R1HDAC8
SCHEMBL28684202 0.79 KDM4E (0.38) ALDH1A1RIPK1TDP1TSHRTAAR1
SCHEMBL4903358 0.77 HTR2A (0.40) ALDH1A1RIPK1TAS1R3TAS1R1HDAC8
SCHEMBL7773019 0.77 S1PR2 (0.45) ALDH1A1TAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108433171-A A kind of selective separation method containing nitroso compound 张宇 2018-08-24 CN disclosed
CN-104053483-B Selective separation of nitroso-containing compounds 英美烟草(投资)有限公司 2016-12-21 CN disclosed