Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 4/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 7/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2484416 | 0.79 | ACHE (0.73) | METAP1ACHEHTR2AHTR2CHTR2B | |
| SCHEMBL6972986 | 0.78 | METAP1 (0.54) | METAP1ACHEHTR2AHTR2CHTR2B | |
| SCHEMBL14939019 | 0.78 | METAP1 (0.54) | METAP1ACHEHTR2AHTR2CHTR2B | |
| SCHEMBL11563001 | 0.78 | METAP1 (0.53) | METAP1HTR2AHTR2CHTR2BAADAT | |
| SCHEMBL15617637 | 0.74 | METAP1 (0.66) | METAP1ACHEHTR2AHTR2CHTR2B | |
| SCHEMBL14339926 | 0.74 | METAP1 (0.50) | METAP1ACHEHTR2AHTR2CHTR2B | |
| SCHEMBL14019342 | 0.74 | METAP1 (0.61) | METAP1ACHEHTR2AHTR2CCYP19A1 | |
| SCHEMBL15617649 | 0.73 | METAP1 (0.49) | METAP1ACHEHTR2AHTR2CHTR2B | |
| SCHEMBL14939596 | 0.73 | CYP19A1 (0.60) | METAP1ACHECYP19A1MAOBELANE | |
| Acetic Acid SCHEMBL28154653 | 0.73 | ACHE (0.63) | METAP1ACHEHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103998422-B | Cyclopentanedione oxime ester and application thereof | 北京英力科技发展有限公司 | 2016-11-30 | — | — | CN | disclosed |