Boric Acid

Boric Acid

SCHEMBL28110899

CN1CCN(c2ccc(OC(C)(C)C(C)(C)O)cn2)CC1.OB(O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 2/20 0.42
FYN P06241 5/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
RAB9A P51151 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
HDAC2 Q92769 1/20 0.38
RET P07949 1/20 0.38
PPARA Q07869 1/20 0.38
TDO2 P48775 1/20 0.37
GPR119 Q8TDV5 1/20 0.36
HRH4 Q9H3N8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL596087 0.79 HTR3A (0.41) HTR3AFYNSMN1; SMN2RAB9AL3MBTL1
Boric Acid SCHEMBL28309975 0.74 HTR3E (0.41) HTR3AL3MBTL1
Boric Acid SCHEMBL27923833 0.73
Boric Acid SCHEMBL28310083 0.72 GAA (0.37) L3MBTL1
SCHEMBL18436092 0.72 OGA (0.54) HTR3ASMN1; SMN2RAB9AL3MBTL1
SCHEMBL27711576 0.70 RAB9A (0.47) HTR3AFYNSMN1; SMN2RAB9AL3MBTL1
SCHEMBL2562848 0.70 HTR3A (0.47) HTR3AFYNSMN1; SMN2RAB9AL3MBTL1
SCHEMBL29516406 0.70 HTR3A (0.47) HTR3AFYNSMN1; SMN2RAB9AL3MBTL1
Boric Acid SCHEMBL28328150 0.70 HPGD (0.56)
SCHEMBL29092810 0.69 ALDH1A1 (0.45) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106167464-A One class quinoline derivatives, Preparation Method And The Use 中国医学科学院药物研究所 2016-11-30 CN disclosed